Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL697563

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of cell growth against HuTu 80 human gastrointestinal adenocarcinoma cell lines in vitro
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HuTu80
Confidence 1 — Organism
Curated By Intermediate

Target

HuTu80 (CHEMBL614582)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis of 5-chloro-5,8-dideaza analogues of folic acid and aminopterin targeted for colon adenocarcinoma.
Hynes JB, Kumar A, Tomazic A, Washtien WL.
J Med Chem (1987) 30 : 1515 -1519
PubMed 3612694 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.35 5.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL36739 1 5.35

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL36739 IC50 = 4500.0 nM 5.35