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Assay Detail

CHEMBL697601

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for inhibition of Interleukin (IL1-beta) release in human monocytes.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

Novel cytokine release inhibitors. Part II: Steroids.
He W, Huang FC, Morytko M, Jariwala N, Yu KT.
Bioorg Med Chem Lett (1998) 8 : 2825 -2828
PubMed 9873630 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.40 7.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL301982 CELASTROL 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL301982 CELASTROL IC50 = 40.0 nM 7.40