Assay Detail
Functional
CHEMBL697602
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for the inhibition of RANTES-induced migration of human monocytes
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Inhibition of RANTES/CCR1-mediated chemotaxis by cosalane and related compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.71 | 6.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3137848 | — | — | 1 | 6.43 |
| CHEMBL3138187 | — | — | 1 | 6.12 |
| CHEMBL3138123 | — | — | 1 | 6.09 |
| CHEMBL3138115 | — | — | 1 | 5.66 |
| CHEMBL3138118 | — | — | 1 | 5.52 |
| CHEMBL3138437 | — | — | 1 | 5.46 |
| CHEMBL3138134 | — | — | 1 | 5.41 |
| CHEMBL3138130 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3137848 | — | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL3138187 | — | IC50 | = | 760.0 | nM | 6.12 |
| CHEMBL3138123 | — | IC50 | = | 820.0 | nM | 6.09 |
| CHEMBL3138115 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL3138118 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3138437 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL3138134 | — | IC50 | = | 3900.0 | nM | 5.41 |
| CHEMBL3138130 | — | IC50 | = | 10000.0 | nM | 5.00 |