Assay Detail
Binding
CHEMBL697801
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Tested for the inhibitory activity of against Ionotropic glutamate receptor AMPA by [3H]- AMPA binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Glutamate receptor ionotropic, AMPA (CHEMBL2093871) ↗| Type | PROTEIN COMPLEX GROUP |
| Organism | Rattus norvegicus |
Publication
Enzymatic resolution of AMPA by use of -chymotrypsin
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.91 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL276815 | (S)-AMPA | — | 1 | 7.70 |
| CHEMBL14815 | — | — | 1 | 4.12 |
| CHEMBL15187 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL276815 | (S)-AMPA | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL14815 | — | IC50 | = | 76000.0 | nM | 4.12 |
| CHEMBL15187 | — | IC50 | > | 100000.0 | nM | - |