Assay Detail
Functional
CHEMBL697870
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Compound was tested for its inhibitory activity against 4 uM ADP-induced platelet aggregation of human platelet rich plasma
7
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Molecular design of novel PGI2 agonists without PG skeleton. IV
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.28 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL430154 | — | — | 1 | 7.58 |
| CHEMBL11746 | — | — | 1 | 7.03 |
| CHEMBL11765 | — | — | 2 | 6.89 |
| CHEMBL275766 | — | — | 1 | 6.17 |
| CHEMBL11480 | — | — | 1 | 5.07 |
| CHEMBL11010 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL430154 | — | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL11746 | — | IC50 | = | 93.0 | nM | 7.03 |
| CHEMBL11765 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL11765 | — | IC50 | = | 530.0 | nM | 6.28 |
| CHEMBL275766 | — | IC50 | = | 670.0 | nM | 6.17 |
| CHEMBL11480 | — | IC50 | = | 8600.0 | nM | 5.07 |
| CHEMBL11010 | — | IC50 | = | 12000.0 | nM | 4.92 |