Assay Detail
Functional
CHEMBL697908
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for inhibition of U-46,619(10 uM) induced platelet aggregation in human platelet rich plasma(PRP).
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Interphenylene 7-oxabicyclo[2.2.1]heptane thromboxane A2 antagonists. Semicarbazone omega-chains.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.42 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95872 | — | — | 1 | 7.92 |
| CHEMBL95884 | — | — | 1 | 7.34 |
| CHEMBL95867 | — | — | 1 | 7.14 |
| CHEMBL318426 | — | — | 1 | 6.15 |
| CHEMBL99041 | — | — | 1 | 5.34 |
| CHEMBL318673 | — | — | 1 | 4.60 |
| CHEMBL99348 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95872 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL95884 | — | IC50 | = | 46.0 | nM | 7.34 |
| CHEMBL95867 | — | IC50 | = | 72.0 | nM | 7.14 |
| CHEMBL318426 | — | IC50 | = | 710.0 | nM | 6.15 |
| CHEMBL99041 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL318673 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL99348 | — | IC50 | = | 133000.0 | nM | - |