Assay Detail
Functional
CHEMBL697909
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for inhibition of arachidonic acid(800 uM) induced platelet aggregation in human platelet rich plasma.
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Interphenylene 7-oxabicyclo[2.2.1]heptane thromboxane A2 antagonists. Semicarbazone omega-chains.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.71 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95872 | — | — | 1 | 8.52 |
| CHEMBL95867 | — | — | 1 | 7.92 |
| CHEMBL95884 | — | — | 1 | 7.82 |
| CHEMBL318426 | — | — | 1 | 6.64 |
| CHEMBL99041 | — | — | 1 | 6.43 |
| CHEMBL318673 | — | — | 1 | 5.14 |
| CHEMBL99348 | — | — | 1 | 4.52 |
| CHEMBL317311 | — | — | 1 | - |
| CHEMBL99349 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95872 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL95867 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL95884 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL318426 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL99041 | — | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL318673 | — | IC50 | = | 7200.0 | nM | 5.14 |
| CHEMBL99348 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL317311 | — | IC50 | = | 688000.0 | nM | - |
| CHEMBL99349 | — | IC50 | = | 310000.0 | nM | - |