Assay Detail
Functional
CHEMBL698063
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Functional selectivity was assessed in a neutrophil chemotaxis assay using N-formyl-methionyl-leucyl-phenylalanine (FMLP)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Nicotinamide N-oxides as CXCR2 antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.93 | 5.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL61835 | — | — | 1 | 5.02 |
| CHEMBL58619 | — | — | 1 | 4.89 |
| CHEMBL294095 | — | — | 1 | 4.88 |
| CHEMBL60066 | — | — | 1 | - |
| CHEMBL62108 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL61835 | — | IC50 | = | 9600.0 | nM | 5.02 |
| CHEMBL58619 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL294095 | — | IC50 | = | 13300.0 | nM | 4.88 |
| CHEMBL60066 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL62108 | — | IC50 | = | - | nM | - |