Assay Detail
Binding
CHEMBL698806
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Inhibitory concentration against human Histone deacetylase 4
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Histone deacetylase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.95 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL146250 | FR-135313 | -1.0 | 1 | 7.60 |
| CHEMBL343448 | ROMIDEPSIN | 4.0 | 1 | 6.29 |
| CHEMBL2093007 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL146250 | FR-135313 | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL343448 | ROMIDEPSIN | IC50 | = | 510.0 | nM | 6.29 |
| CHEMBL2093007 | — | IC50 | = | 110000.0 | nM | - |