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Assay Detail

CHEMBL698826

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for inhibitory concentration potent against IMPDH type-I
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

Chemical synthesis of benzamide adenine dinucleotide: inhibition of inosine monophosphate dehydrogenase (types I and II).
Zatorski A, Watanabe KA, Carr SF, Goldstein BM, Pankiewicz KW.
J Med Chem (1996) 39 : 2422 -2426
PubMed 8691436 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.03 7.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL108358 TIAZOFURIN 2.0 1 7.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL108358 TIAZOFURIN IC50 = 94.0 nM 7.03