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Assay Detail

CHEMBL698829

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of IL-2 production in whole blood assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Tissue Blood
Confidence 1 — Organism
Curated By Expert

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
Calderwood DJ, Johnston DN, Munschauer R, Rafferty P.
Bioorg Med Chem Lett (2002) 12 : 1683 -1686
PubMed 12039590 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.16 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL47203 1 7.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL47203 IC50 = 70.0 nM 7.16