Assay Detail
Functional
CHEMBL699000
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In vitro inhibition of ADP (0.5 x 10E-9 M)-induced platelet aggregation in human PRP
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of a new chemically and metabolically stable prostacyclin analogue with high and long-lasting oral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.15 | 9.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL323744 | — | — | 1 | 9.19 |
| CHEMBL1139 | EPOPROSTENOL | 4.0 | 1 | 9.18 |
| CHEMBL494 | ILOPROST | 4.0 | 1 | 9.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL323744 | — | IC50 | = | 0.64 | nM | 9.19 |
| CHEMBL1139 | EPOPROSTENOL | IC50 | = | 0.66 | nM | 9.18 |
| CHEMBL494 | ILOPROST | IC50 | = | 0.82 | nM | 9.09 |