Assay Detail
Functional
CHEMBL699002
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of thrombin (0.14 IU/mL)-induced platelet aggregation in human PRP
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of a new chemically and metabolically stable prostacyclin analogue with high and long-lasting oral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.65 | 9.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL323744 | — | — | 1 | 9.89 |
| CHEMBL494 | ILOPROST | 4.0 | 1 | 9.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL323744 | — | IC50 | = | 0.13 | nM | 9.89 |
| CHEMBL494 | ILOPROST | IC50 | = | 0.39 | nM | 9.41 |