Assay Detail
Functional
CHEMBL699130
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of insulin receptor mediated mitogenesis of NIH3T3 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Naamidine A is an antagonist of the epidermal growth factor receptor and an in vivo active antitumor agent.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.09 | 5.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL340520 | — | — | 1 | 5.17 |
| CHEMBL339550 | — | — | 1 | 5.01 |
| CHEMBL339727 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL340520 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL339550 | — | IC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL339727 | — | IC50 | = | 242000.0 | nM | - |