Assay Detail
Binding
CHEMBL699291
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Ability to inhibit IL-1 beta converting enzyme was evaluated in LPS-stimulated human whole blood
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Blood |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Peptidyl beta-homo-aspartals: specific inhibitors of interleukin-1 beta converting enzyme and its homologues (caspases).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.62 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL37630 | — | — | 1 | 5.70 |
| CHEMBL34031 | — | — | 1 | 5.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL37630 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL34031 | — | IC50 | = | 2900.0 | nM | 5.54 |