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Assay Detail

CHEMBL699327

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was tested in vitro for growth inhibition against HeLa(human cervix adenocarcinoma) cell line in the dark
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Intermediate

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

New tetracyclic analogues of photochemotherapeutic drugs 5-MOP and 8-MOP: synthesis, DNA interaction, and antiproliferative activity.
Dalla Via L, Gia O, Marciani Magno S, Santana L, Teijeira M, Uriarte E.
J Med Chem (1999) 42 : 4405 -4413
PubMed 10543884 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 14 5.02 5.02

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL136584 1 5.02
CHEMBL138845 1 -
CHEMBL345061 1 -
CHEMBL341689 1 -
CHEMBL336233 1 -
CHEMBL136386 1 -
CHEMBL138134 1 -
CHEMBL136473 1 -
CHEMBL138512 1 -
CHEMBL342425 1 -
CHEMBL24171 BERGAPTEN 3.0 1 -
CHEMBL416 METHOXSALEN 4.0 1 -
CHEMBL138861 1 -
CHEMBL345062 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL136584 IC50 = 9600.0 nM 5.02
CHEMBL138845 IC50 > 20000.0 nM -
CHEMBL345061 IC50 > 20000.0 nM -
CHEMBL341689 IC50 > 20000.0 nM -
CHEMBL336233 IC50 > 20000.0 nM -
CHEMBL136386 IC50 > 20000.0 nM -
CHEMBL138134 IC50 > 20000.0 nM -
CHEMBL136473 IC50 > 20000.0 nM -
CHEMBL138512 IC50 > 20000.0 nM -
CHEMBL342425 IC50 > 20000.0 nM -
CHEMBL24171 BERGAPTEN IC50 > 20000.0 nM -
CHEMBL416 METHOXSALEN IC50 > 20000.0 nM -
CHEMBL138861 IC50 > 20000.0 nM -
CHEMBL345062 IC50 > 20000.0 nM -