Compound Detail
CHEMBL345061
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Basic Information
| ChEMBL ID | CHEMBL345061 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RZQZKJSZNMFWIH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
280.3
MW (Da)
4.01
ALogP
4
HBA
0
HBD
52.6
PSA (Ų)
0.49
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HL-60 CHEMBL383 | IC50 | 5.19 | 5.19 | 6400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HL-60 | IC50 | = | 6400.0 | nM | 5.19 | The compound was tested in vitro for growth inhibition against HL-60(human promy... | 10543884 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10543884 | 10.1021/jm9910829 | HeLa | 2 |
| 10543884 | 10.1021/jm9910829 | HL-60 | 2 |
| 10543884 | 10.1021/jm9910829 | Cavia porcellus | 1 |
Data from ChEMBL 36 via Core Engine