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Assay Detail

CHEMBL699346

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was tested for inhibitory activity against 5-Lipoxygenase in human polymorphonuclear leukocytes[PMNS]
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
Musser JH, Kreft AF.
J Med Chem (1992) 35 : 2501 -2524
PubMed 1635053 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.60 8.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL29097 1 8.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL29097 IC50 = 2.5 nM 8.60