Assay Detail
Binding
CHEMBL699599
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Binding affinity towards inducible nitric oxide synthase (iNOS)
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Potent and selective conformationally restricted neuronal nitric oxide synthase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.12 | 4.54 |
| Ki | 1 | 4.60 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL44833 | — | — | 1 | 4.60 |
| CHEMBL161297 | — | — | 1 | 4.54 |
| CHEMBL1169419 | — | — | 1 | 3.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL44833 | — | Ki | = | 25000.0 | nM | 4.60 |
| CHEMBL161297 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL1169419 | — | IC50 | = | 199000.0 | nM | 3.70 |