Assay Detail
Binding
CHEMBL699687
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for inhibition of mouse inducible nitric oxide synthase
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.28 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL227744 | NITROARGININE | 1.0 | 1 | 6.30 |
| CHEMBL7889 | L-NIL | — | 1 | 5.48 |
| CHEMBL11471 | L-NIO | — | 1 | 5.41 |
| CHEMBL256147 | TILARGININE | 3.0 | 1 | 5.08 |
| CHEMBL127739 | — | — | 1 | 4.14 |
| CHEMBL340800 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL227744 | NITROARGININE | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL7889 | L-NIL | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL11471 | L-NIO | IC50 | = | 3900.0 | nM | 5.41 |
| CHEMBL256147 | TILARGININE | IC50 | = | 8300.0 | nM | 5.08 |
| CHEMBL127739 | — | IC50 | = | 73000.0 | nM | 4.14 |
| CHEMBL340800 | — | IC50 | = | 336000.0 | nM | - |