Assay Detail
Functional
CHEMBL699805
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Compound was tested in vitro inhibitory activity against human neutrophil CD11b/CD18.
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Modulators of leukotriene biosynthesis and receptor activation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.20 | 8.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL292782 | — | — | 1 | 8.92 |
| CHEMBL329123 | ETALOCIB | 2.0 | 1 | 8.41 |
| CHEMBL88337 | — | — | 1 | 7.33 |
| CHEMBL90788 | — | — | 1 | 5.80 |
| CHEMBL15766 | LY-255283 | — | 1 | 5.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL292782 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL329123 | ETALOCIB | IC50 | = | 3.9 | nM | 8.41 |
| CHEMBL88337 | — | IC50 | = | 47.0 | nM | 7.33 |
| CHEMBL90788 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL15766 | LY-255283 | IC50 | = | 2874.0 | nM | 5.54 |