Assay Detail
Functional
CHEMBL700006
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cellular activity by neutrophil assay
10
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Potent and selective PKC inhibitory 5-membered ring analogs of balanol with replacement of the carboxamide moiety
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.62 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL48665 | — | — | 1 | 6.58 |
| CHEMBL295806 | — | — | 2 | 5.51 |
| CHEMBL48546 | — | — | 1 | 5.37 |
| CHEMBL48636 | — | — | 1 | - |
| CHEMBL49354 | — | — | 2 | - |
| CHEMBL300422 | — | — | 1 | - |
| CHEMBL265559 | — | — | 1 | - |
| CHEMBL48988 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL48665 | — | IC50 | = | 260.0 | nM | 6.58 |
| CHEMBL295806 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL48546 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL295806 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL48636 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL49354 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL300422 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL265559 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL49354 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL48988 | — | IC50 | > | 10000.0 | nM | - |