Assay Detail
Binding
CHEMBL700570
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for binding affinity towards Inositol-1,4,5-trisphosphate 5-phosphatase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Inositol polyphosphate-5-phosphatase A (CHEMBL4243) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Total synthesis of L-2,2-difluoro-2-deoxy-MYO-inositol 1,4,5-trisphosphate, a potent inhibitor of the enzymes of d-MYO-inositol 1,4,5-trisphosphate metabolism
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 4.58 | 4.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1161466 | — | — | 1 | 4.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1161466 | — | Ki | = | 26000.0 | nM | 4.58 |