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Assay Detail

CHEMBL700571

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was evaluated for inhibition of Inositol-1,4,5-trisphosphate 5-phosphatase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Inositol polyphosphate-5-phosphatase A (CHEMBL4243)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Total synthesis of myo-inositol-1-phosphate-4,5-pyrophosphate, a novel second messenger analogue, via myo-inositol-1-phosphate-4,5-bisphosphorothioate
Noble NJ, Dubreuil D, Potter B
Bioorg Med Chem Lett (1992) 2 : 471 -476
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.89 5.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1161242 1 5.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1161242 Ki = 1300.0 nM 5.89