Assay Detail
Functional
CHEMBL700623
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Cytotoxicity against uninfected human foreskin fibroblast(HFF cells)
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Synthesis and antiviral activity of certain 4- and 4,5-disubstituted 7-[(2-hydroxyethoxy)methyl]pyrrolo[2,3-d]pyrimidines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.07 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL610074 | — | — | 1 | 5.70 |
| CHEMBL99203 | IODOTUBERCIDIN | — | 1 | 5.70 |
| CHEMBL3126906 | — | — | 1 | 5.70 |
| CHEMBL62099 | — | — | 1 | 5.35 |
| CHEMBL98933 | — | — | 1 | 5.00 |
| CHEMBL1688967 | IMMUNICILLIN H | — | 1 | 5.00 |
| CHEMBL328824 | — | — | 1 | 4.89 |
| CHEMBL612156 | — | — | 1 | 4.51 |
| CHEMBL610644 | — | — | 1 | 4.51 |
| CHEMBL403715 | — | — | 1 | 4.34 |
| CHEMBL610642 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL610074 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL99203 | IODOTUBERCIDIN | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL3126906 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL62099 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL98933 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1688967 | IMMUNICILLIN H | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL328824 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL612156 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL610644 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL403715 | — | IC50 | = | 46000.0 | nM | 4.34 |
| CHEMBL610642 | — | IC50 | > | 100000.0 | nM | - |