Assay Detail
Functional
CHEMBL700625
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration of the drug against the cytopathic effect for AD169 strain of epstein barr virus-2 (HCMV) in human HFF cells
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antiviral activity of novel 5-(1-azido-2-haloethyl) and 5-(1-azido-, amino-, or methoxyethyl) analogs of 2'-deoxyuridine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 5.55 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 6.30 |
| CHEMBL318153 | EDOXUDINE | 2.0 | 1 | 6.05 |
| CHEMBL3142422 | — | — | 1 | 5.23 |
| CHEMBL223205 | — | — | 1 | 4.61 |
| CHEMBL3143951 | — | — | 1 | - |
| CHEMBL3142421 | — | — | 1 | - |
| CHEMBL3142424 | — | — | 1 | - |
| CHEMBL3142423 | — | — | 1 | - |
| CHEMBL3142425 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL182 | GANCICLOVIR | EC50 | = | 500.0 | nM | 6.30 |
| CHEMBL318153 | EDOXUDINE | EC50 | = | 900.0 | nM | 6.05 |
| CHEMBL3142422 | — | EC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL223205 | — | EC50 | = | 24800.0 | nM | 4.61 |
| CHEMBL3143951 | — | EC50 | > | 125000.0 | nM | - |
| CHEMBL3142421 | — | EC50 | > | 118000.0 | nM | - |
| CHEMBL3142424 | — | EC50 | > | 170000.0 | nM | - |
| CHEMBL3142423 | — | EC50 | > | 150000.0 | nM | - |
| CHEMBL3142425 | — | EC50 | > | 130000.0 | nM | - |