Assay Detail
Binding
CHEMBL700650
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration required for 50% inhibition of Inositol monophosphatase
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of myo-inositol monophosphatase unrelated to the enzyme substrate
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.78 | 6.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL347446 | — | — | 1 | 6.21 |
| CHEMBL156571 | — | — | 1 | 4.64 |
| CHEMBL159230 | — | — | 1 | 4.54 |
| CHEMBL348519 | — | — | 1 | 4.44 |
| CHEMBL56556 | — | — | 1 | 4.42 |
| CHEMBL157667 | — | — | 1 | 4.40 |
| CHEMBL350677 | — | — | 1 | - |
| CHEMBL871 | ETIDRONIC ACID | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL347446 | — | IC50 | = | 610.0 | nM | 6.21 |
| CHEMBL156571 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL159230 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL348519 | — | IC50 | = | 36000.0 | nM | 4.44 |
| CHEMBL56556 | — | IC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL157667 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL350677 | — | IC50 | = | 140000.0 | nM | - |
| CHEMBL871 | ETIDRONIC ACID | IC50 | = | 110000.0 | nM | - |