Compound Detail
CHEMBL347446
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Basic Information
| ChEMBL ID | CHEMBL347446 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GDOHSOOXTKYNBT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
414.3
MW (Da)
2.82
ALogP
4
HBA
5
HBD
144.5
PSA (Ų)
0.47
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Inositol monophosphatase 1 CHEMBL4505 | IC50 | 6.21 | 6.21 | 610.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Inositol monophosphatase 1 | IC50 | = | 610.0 | nM | 6.21 | Concentration required for 50% inhibition of Inositol monophosphatase | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(01)81212-9 | Inositol monophosphatase 1 | 1 |
Data from ChEMBL 36 via Core Engine