Assay Detail

CHEMBL700822

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Functional

Tested for ability to inhibit arachidonic acid-induced and ADP-induced platelet aggregation of human platelet rich plasma

ChEMBL ↗

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Target

Homo sapiens (CHEMBL372) ↗

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Primary target Homo sapiens

CHEMBL372

Anchored from Assay target.

Protein identity Homo sapiens

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Tissue	Plasma
Confidence	1 — Organism
Curated By	Intermediate

Target

Homo sapiens (CHEMBL372) ↗

Type	ORGANISM
Organism	Homo sapiens

Publication

Thoromboxane A2/endoperoxide receptor antagonists: 1,3-Dioxane and 1,3-dioxolane analogs

Das J, Reid JA, Harris DN, Goldenberg H, Michel IM, Monshizadegan H, Webb ML
Bioorg Med Chem Lett (1993) 3 : 1271 -1276
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.15	8.15

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL283100	BMS-180291	—	1	8.15

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL283100	BMS-180291	IC50	=	7.0	nM	8.15