Assay Detail
Functional
CHEMBL700849
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Cytotoxicity of compound was determined by assaying cell growth in human neoplastic cell line(KB).
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, antiproliferative, and antiviral activity of certain 4-aminopyrrolo[2,3-d]pyridazine nucleosides: an entry into a novel series of adenosine analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.48 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267099 | TUBERCIDIN | — | 1 | 6.00 |
| CHEMBL62099 | — | — | 1 | 5.52 |
| CHEMBL611541 | — | — | 1 | 4.92 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | - |
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267099 | TUBERCIDIN | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL62099 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL611541 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL182 | GANCICLOVIR | IC50 | > | 100000.0 | nM | - |
| CHEMBL184 | ACYCLOVIR | IC50 | > | 100000.0 | nM | - |