Assay Detail
ADMET
CHEMBL700852
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Cytotoxic activity against KB cells.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | Neoplastic cell line |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, antiproliferative, and antiviral activity of certain 4-substituted and 4,5-disubstituted 7-[(1,3-dihydroxy-2-propoxy)methyl]pyrrolo[2,3-d]pyrimidines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.64 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL62099 | — | — | 1 | 5.64 |
| CHEMBL61716 | — | — | 1 | - |
| CHEMBL291375 | — | — | 1 | - |
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL62099 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL61716 | — | IC50 | = | 320000.0 | nM | - |
| CHEMBL291375 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL184 | ACYCLOVIR | IC50 | > | 100000.0 | nM | - |