Assay Detail
Functional
CHEMBL700876
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The compound was tested for the inhibition of platelet aggregation
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Nonpeptide GPIIB/IIIA inhibitors. 16. Thieno[2,3-b]thiophene -sulfonamides are potent inhibitors of platelet aggregation
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 7.59 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL293601 | — | — | 1 | 8.10 |
| CHEMBL78760 | — | — | 1 | 8.10 |
| CHEMBL78570 | — | — | 1 | 8.10 |
| CHEMBL78503 | — | — | 1 | 8.05 |
| CHEMBL312113 | — | — | 1 | 8.00 |
| CHEMBL80432 | — | — | 1 | 7.96 |
| CHEMBL78517 | — | — | 1 | 7.89 |
| CHEMBL310964 | — | — | 1 | 7.68 |
| CHEMBL169796 | — | — | 1 | 7.64 |
| CHEMBL80381 | — | — | 1 | 7.50 |
| CHEMBL352847 | — | — | 1 | 7.44 |
| CHEMBL355050 | — | — | 1 | 7.12 |
| CHEMBL312330 | — | — | 1 | 6.39 |
| CHEMBL80307 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL293601 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL78760 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL78570 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL78503 | — | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL312113 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL80432 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL78517 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL310964 | — | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL169796 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL80381 | — | IC50 | = | 32.0 | nM | 7.50 |
| CHEMBL352847 | — | IC50 | = | 36.0 | nM | 7.44 |
| CHEMBL355050 | — | IC50 | = | 76.0 | nM | 7.12 |
| CHEMBL312330 | — | IC50 | = | 410.0 | nM | 6.39 |
| CHEMBL80307 | — | IC50 | = | 500.0 | nM | 6.30 |