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Assay Detail

CHEMBL701424

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against IL-1 beta converting enzyme was evaluated.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Caspase-1 (CHEMBL4801)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Novel cytokine release inhibitors. Part I: Triterpenes.
Huang FC, Chan WK, Moriarty KJ, Zhang DC, Chang MN, He W, Yu KT, Zilberstein A.
Bioorg Med Chem Lett (1998) 8 : 1883 -1886
PubMed 9873452 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL8320 BENZOQUINONE 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL8320 BENZOQUINONE IC50 = 3000.0 nM 5.52