Assay Detail
Functional
CHEMBL701606
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Inhibition of KB cell growth was assessed
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Deoxy sugar analogues of triciribine: correlation of antiviral and antiproliferative activity with intracellular phosphorylation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.90 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL462018 | TRICIRIBINE PHOSPHATE | 2.0 | 1 | 5.00 |
| CHEMBL1790617 | — | — | 1 | 4.80 |
| CHEMBL314567 | — | — | 1 | - |
| CHEMBL2367598 | — | — | 1 | - |
| CHEMBL2112098 | — | — | 1 | - |
| CHEMBL331237 | TRICIRIBINE | — | 1 | - |
| CHEMBL315509 | — | — | 1 | - |
| CHEMBL609194 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL462018 | TRICIRIBINE PHOSPHATE | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1790617 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL314567 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2367598 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2112098 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL331237 | TRICIRIBINE | IC50 | > | 100000.0 | nM | - |
| CHEMBL315509 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL609194 | — | IC50 | > | 100000.0 | nM | - |