Assay Detail
Functional
CHEMBL701916
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Calcium Ionophore (A-23187)-stimulated LTB4 formation in Human whole blood assay.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Blood |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Heteroarylmethoxyphenylalkoxyiminoalkylcarboxylic acids as leukotriene biosynthesis inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.33 | 6.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2110174 | — | — | 1 | 6.14 |
| CHEMBL2093045 | — | — | 1 | 6.08 |
| CHEMBL159721 | — | — | 1 | 5.75 |
| CHEMBL2110175 | — | — | 1 | 5.68 |
| CHEMBL1788266 | — | — | 1 | 4.20 |
| CHEMBL159590 | — | — | 1 | 4.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2110174 | — | IC50 | = | 720.0 | nM | 6.14 |
| CHEMBL2093045 | — | IC50 | = | 840.0 | nM | 6.08 |
| CHEMBL159721 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL2110175 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL1788266 | — | IC50 | = | 63000.0 | nM | 4.20 |
| CHEMBL159590 | — | IC50 | = | 72000.0 | nM | 4.14 |