Assay Detail
Functional
CHEMBL701935
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Comparative inhibition of L5178Y cell growth in vitro (concentration required for 50% inhibition)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L5178Y |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological activity of 5-fluoro-2'-deoxyuridine 5'-phosphorodiamidates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.89 | 9.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL917 | FLOXURIDINE | 4.0 | 1 | 9.12 |
| CHEMBL886 | 5-FLUORODEOXYURIDYLATE | — | 1 | 8.85 |
| CHEMBL3143430 | — | — | 1 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL917 | FLOXURIDINE | IC50 | = | 0.76 | nM | 9.12 |
| CHEMBL886 | 5-FLUORODEOXYURIDYLATE | IC50 | = | 1.4 | nM | 8.85 |
| CHEMBL3143430 | — | IC50 | = | 2.0 | nM | 8.70 |