Assay Detail
Functional
CHEMBL701986
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Compound was evaluated for inhibition of Interleukin (IL1-beta) release in human monocytes.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel cytokine release inhibitors. Part II: Steroids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.24 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL292578 | PRISTIMEROL DIACETATE | — | 1 | 7.10 |
| CHEMBL328500 | — | — | 1 | 6.82 |
| CHEMBL96756 | — | — | 1 | 5.52 |
| CHEMBL419509 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL292578 | PRISTIMEROL DIACETATE | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL328500 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL96756 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL419509 | — | IC50 | = | 3000.0 | nM | 5.52 |