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Assay Detail

CHEMBL702439

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Functional
Inhibition against human neoplastic cell line(KB cells)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type KB
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

Synthesis and antiviral activity of certain 4- and 4,5-disubstituted 7-[(2-hydroxyethoxy)methyl]pyrrolo[2,3-d]pyrimidines.
Pudlo JS, Saxena NK, Nassiri MR, Turk SR, Drach JC, Townsend LB.
J Med Chem (1988) 31 : 2086 -2092
PubMed 2846837 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.01 6.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL63282 1 6.09
CHEMBL63224 1 5.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL63282 IC50 = 820.0 nM 6.09
CHEMBL63224 IC50 = 1200.0 nM 5.92