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Assay Detail

CHEMBL703077

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for its ability to inhibit the growth of a clinical strain of Klebsiella pneumoniae at 0.01 ng/mL
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Klebsiella pneumoniae
Confidence 1 — Organism
Curated By Intermediate

Target

Klebsiella pneumoniae (CHEMBL350)
Type ORGANISM
Organism Klebsiella pneumoniae

Publication

Synthesis and testing of substituted phenylthioribose analogs against Klebsiella pneumoniae
Winter R, Cornell KA, Johnson LL, Riscoe MK
Bioorg Med Chem Lett (1993) 3 : 2079 -2082
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 7.68 10.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL609180 1 10.30
CHEMBL611521 1 6.43
CHEMBL611234 1 6.30
CHEMBL610936 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL609180 IC50 = 0.05 nM 10.30
CHEMBL611521 IC50 = 375.0 nM 6.43
CHEMBL611234 IC50 = 500.0 nM 6.30
CHEMBL610936 IC50 = 0.0025 nM -