Assay Detail
Binding
CHEMBL703266
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Dissociation constant for Leukocyte function associated antigen 1 (LFA-1)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 6 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Intercellular adhesion molecule (ICAM-1), Integrin alpha-L/beta-2 (CHEMBL2096661) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
Fragment-based drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 2.76 | 3.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL15844 | INDOLE | — | 1 | 3.52 |
| CHEMBL19452 | — | — | 1 | 2.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL15844 | INDOLE | Kd | = | 300000.0 | nM | 3.52 |
| CHEMBL19452 | — | Kd | = | 10000000.0 | nM | 2.00 |