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Assay Detail

CHEMBL703952

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Concentration of the drug to inhibit L1210 leukemia cell growth in culture
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Cell Type L1210
Confidence 1 — Organism
Curated By Intermediate

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

DNA-directed alkylating agents. 6. Synthesis and antitumor activity of DNA minor groove-targeted aniline mustard analogues of pibenzimol (Hoechst 33258)
Gravatt GL, Baguley BC, Wilson WR, Denny WA.
J Med Chem (1994) 37 : 4338 -4345
PubMed 7527862 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL139109 (+)-CC-1065 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL139109 (+)-CC-1065 IC50 = 3000.0 nM 5.52