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Assay Detail

CHEMBL704424

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of binding of [3H]LTB4 to receptor on nonradioactive LTB4
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Leukotriene B4 receptor 1 (CHEMBL3911)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists.
Jackson WT, Boyd RJ, Froelich LL, Gapinski DM, Mallett BE, Sawyer JS.
J Med Chem (1993) 36 : 1726 -1734
PubMed 8389876 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.72 8.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL49302 1 8.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL49302 IC50 = 1.9 nM 8.72