Assay Detail
Binding
CHEMBL704426
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Inhibition of specific binding of [3H]LTB4 to Leukotriene B4 receptor in human neutrophils
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Benzophenone dicarboxylic acid antagonists of leukotriene B4. 2. Structure-activity relationships of the lipophilic side chain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.30 | 8.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL65061 | LEUKOTRIENE_B4 | — | 1 | 8.72 |
| CHEMBL49302 | — | — | 1 | 7.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL65061 | LEUKOTRIENE_B4 | IC50 | = | 1.9 | nM | 8.72 |
| CHEMBL49302 | — | IC50 | = | 13.2 | nM | 7.88 |