Assay Detail
Functional
CHEMBL704561
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for inhibition of L1210 cell growth by the compound after 96 hr
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthetic polyamine analogues as antineoplastics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.99 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18794 | BIS(ETHYL)SPERMINE | — | 1 | 7.00 |
| CHEMBL18111 | — | — | 1 | 6.70 |
| CHEMBL18083 | — | — | 1 | 6.30 |
| CHEMBL274477 | — | — | 1 | 6.12 |
| CHEMBL18610 | — | — | 1 | 5.52 |
| CHEMBL18385 | — | — | 1 | 5.30 |
| CHEMBL18027 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18794 | BIS(ETHYL)SPERMINE | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL18111 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL18083 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL274477 | — | IC50 | = | 750.0 | nM | 6.12 |
| CHEMBL18610 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL18385 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL18027 | — | IC50 | = | 10000.0 | nM | 5.00 |