Assay Detail
Functional
CHEMBL705076
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophils
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.59 | 6.88 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL49210 | — | — | 1 | 6.88 |
| CHEMBL288758 | — | — | 1 | 6.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL49210 | — | IC50 | = | 133.0 | nM | 6.88 |
| CHEMBL288758 | — | IC50 | = | 513.0 | nM | 6.29 |