Assay Detail
Binding
CHEMBL706220
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CB
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.85 | 5.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL422 | TRIFLUOPERAZINE | 4.0 | 1 | 5.05 |
| CHEMBL6665 | — | — | 1 | 5.01 |
| CHEMBL28 | APIGENIN | — | 1 | 4.75 |
| CHEMBL6694 | — | — | 1 | 4.58 |
| CHEMBL7054 | — | — | 1 | - |
| CHEMBL294878 | — | — | 1 | - |
| CHEMBL7348 | THERALIN | — | 1 | - |
| CHEMBL1159471 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL422 | TRIFLUOPERAZINE | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL6665 | — | IC50 | = | 9700.0 | nM | 5.01 |
| CHEMBL28 | APIGENIN | IC50 | = | 17700.0 | nM | 4.75 |
| CHEMBL6694 | — | IC50 | = | 26300.0 | nM | 4.58 |
| CHEMBL7054 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL294878 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL7348 | THERALIN | IC50 | > | 30000.0 | nM | - |
| CHEMBL1159471 | — | IC50 | > | 30000.0 | nM | - |