Compound Detail
CHEMBL6694
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL6694 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZCTNPCRBEWXCGP-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
270.2
MW (Da)
2.58
ALogP
5
HBA
3
HBD
90.9
PSA (Ų)
0.63
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | IC50 | 4.6 | 4.6 | 25100.0 | 1 |
| Lysozyme C CHEMBL2297 | IC50 | 4.58 | 4.58 | 26300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | IC50 | = | 25100.0 | nM | 4.6 | Inhibitory effect of compound on superoxide anion generation in rat neutrophils ... | 15013012 |
| Lysozyme C | IC50 | = | 26300.0 | nM | 4.58 | Inhibitory effect of compound on the release of lysozyme in rat neutrophils stim... | 15013012 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15013012 | 10.1016/j.bmcl.2003.11.074 | Rattus norvegicus | 2 |
| 15013012 | 10.1016/j.bmcl.2003.11.074 | Mus musculus | 2 |
| 15013012 | 10.1016/j.bmcl.2003.11.074 | Beta-glucuronidase | 1 |
| 15013012 | 10.1016/j.bmcl.2003.11.074 | Lysozyme C | 1 |
Data from ChEMBL 36 via Core Engine