Assay Detail
Functional
CHEMBL783512
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Inhibitory effect of compound on superoxide anion generation in rat neutrophils stimulated with fMLP/CB
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.08 | 5.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL28 | APIGENIN | — | 1 | 5.47 |
| CHEMBL422 | TRIFLUOPERAZINE | 4.0 | 1 | 5.18 |
| CHEMBL6694 | — | — | 1 | 4.60 |
| CHEMBL6665 | — | — | 1 | - |
| CHEMBL7054 | — | — | 1 | - |
| CHEMBL294878 | — | — | 1 | - |
| CHEMBL7348 | THERALIN | — | 1 | - |
| CHEMBL1159471 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL28 | APIGENIN | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL422 | TRIFLUOPERAZINE | IC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL6694 | — | IC50 | = | 25100.0 | nM | 4.60 |
| CHEMBL6665 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL7054 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL294878 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL7348 | THERALIN | IC50 | > | 30000.0 | nM | - |
| CHEMBL1159471 | — | IC50 | > | 30000.0 | nM | - |