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Assay Detail

CHEMBL707052

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested to inhibit HIV-1 replication in MT-4 cell lines; value may range from 1 - 10
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MT4
Confidence 1 — Organism
Curated By Intermediate

Target

MT4 (CHEMBL388)
Type CELL-LINE
Organism Homo sapiens

Publication

Modelisation, synthesis and antiviral evaluation of new 2,3-disubstituted thiazolidinone nucleoside analogues
Graciet J, Niddam V, Gamberoni M, Trabaud C, Dessolin J, Medou M, Mourier N, Zoulim F, Borel C, Hantz O, Camplo M, Chermann J, Kraus J
Bioorg Med Chem Lett (1996) 6 : 1775 -1780
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL297708 1 5.00
CHEMBL50289 1 5.00
CHEMBL52288 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL297708 IC50 = 10000.0 nM 5.00
CHEMBL50289 IC50 = 10000.0 nM 5.00
CHEMBL52288 IC50 = 10000.0 nM 5.00