Assay Detail
Functional
CHEMBL707128
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Inhibition of L1210 lymphoid leukemia cells 24 hr after administration (length of preincubation=0 hr)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and functional evaluation of a peptide derivative of 1-beta-D-arabinofuranosylcytosine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.00 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3350436 | — | — | 1 | 8.00 |
| CHEMBL803 | CYTARABINE | 4.0 | 1 | 7.00 |
| CHEMBL3350527 | — | — | 1 | 7.00 |
| CHEMBL3350435 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3350436 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL803 | CYTARABINE | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL3350527 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL3350435 | — | IC50 | = | 1000.0 | nM | 6.00 |